Non sedating antipsychotic medicatoin
This list of the atypical antipsychotics provides links to drug safety information from the drug manufacturers' websites.Antipsychotics all have some antihistaminic properties. Almost all antipsychotics are associated with some weight gain.Anticholinergic effects are especially prominent with weaker-binding first-generation antipsychotics, as well as with the second-generation antipsychotic clozapine.
These drugs, the atypical antipsychotics, have proven generally as effective as the antipsychotics developed decades earlier, with fewer extrapyramidal side effects.
In many cases, these medicines are used for “off-label” indications and this is a worrying trend given their potential for significant metabolic adverse effects.
Antipsychotics are indicated for the treatment of schizophrenia and related disorders and in some circumstances to treat the behavioural and psychological symptoms associated with dementia (risperidone only).
The newer second-generation antipsychotics, especially clozapine and olanzapine, generally tend to cause more problems relating to metabolic syndrome, such as obesity and type 2 diabetes mellitus.
Also, as a class, the older first-generation antipsychotics are more likely to be associated with movement disorders, but this is primarily true of medications that bind tightly to dopaminergic neuroreceptors, such as haloperidol, and less true of medications that bind weakly, such as chlorpromazine.
Older antidepressants, such as TCAs and monoamine oxidase inhibitors (MAOIs), also are effective in the treatment of some anxiety disorders.